Top Rated Weed Businesses in Sioux Falls, South Dakota (2026)
The highest-rated weed-related businesses in Sioux Falls, South Dakota, ranked by customer reviews and overall rating. Updated 2026-05-20.
- #1
Genesis Farms Cannabis Dispensary
3601 S Minnesota Ave A, Sioux Falls, SD 57105, USA
Cannabis store"this place has friendly staff and always has good deals."
— ryan wagner - #2
East River Farms Medical Dispensary
3613 W Avera Dr Suite 3, Sioux Falls, SD 57108, USA
Cannabis store"As soon as I walked in every worker welcomed me and made it feel so homey and personable. My budtender Jodi made my first time there feel like I’ve been a regular (I’m from out of town) but I will..."
— Kelsey Smith - #3
Roy'zzz Premium Cannabis
2520 S Louise Ave, Sioux Falls, SD 57106, USA
Cannabis store"Every time I have visited Roy'zzz I've had an absolutely AMAZING experience! The staff are super friendly, extremely knowledgeable, and incredibly helpful! I appreciate how patient they are, and I..."
— Kayla Odell - #4
Genesis Farms Cannabis Dispensary
7401 E Arrowhead Pkwy Suite 200, Sioux Falls, SD 57110, USA
Cannabis store"I went in my first time and the entire staff was so helpful and kind. I have been there quite a few times since my first time and it is always such a pleasant shopping experience with them. They..."
— Kayli Peters - #5
The Cannabis Factory
825 S Minnesota Ave, Sioux Falls, SD 57104, USA
Cannabis store"Very convenient right in my neighborhood. Always a great selection and great customer service. Tateum is very knowledgeable with the different strands that are best."
— Matt - #6
Flower Shop Dispensary
2211 W 49th St, Sioux Falls, SD 57105, USA
Cannabis store"The Flower Shop carries some of the best strains in the area! They have a huge variety as well. Seriously something for everyone!! Fair prices, and they offer different deals and specials every week...."
— Cassidy Cleland-Nissen - #7
CannaCare Medical Dispensary
3215 S Carolyn Ave, Sioux Falls, SD 57106, USA
Cannabis store"Joey and the staff here are prompt, polite and knowledgable. Always showed the best side of wanting whats best for the patient, me."
— Anthony Cook
How We Rank Listings in Sioux Falls
Our top-rated list is based on customer ratings and review volume. Sponsored listings do not influence rankings on this page. Businesses are ranked by average Google rating, with review count used as a tiebreaker.