Substance
About Substance
Found at 1749 E McAndrews Rd, Substance is a smaller-footprint dispensary in Medford with a 4.8-star average from 32 reviews — early signs of a shop dialing in fast. Reviewers describe the space as big, clean, and welcoming, with budtenders like Erika and Casey getting named for friendly, patient service. Mac n Jack and Capped Out flower come up specifically, alongside concentrates that fans call "absolutely bomb." Substance has multiple locations in Oregon, and customers traveling between them mention the consistency across stores. Hours run 8 AM to 9 PM Monday through Friday, with 9 AM to 9 PM on weekends. The McAndrews location is a quick stop if you're moving through east Medford. Smaller review pool means impressions are still forming, but the early signal is strong — clean shop, knowledgeable staff, fair prices, and a wide enough selection to keep regulars coming back.
- Clean welcoming environment
- Friendly, patient staff
- Solid concentrate selection
- Multi-location consistency
Photos
Business Details
- Address
- 1749 E McAndrews Rd, Medford, OR 97504, USA
- State
- Oregon
- Phone
- (541) 317-1814
- Int'l Phone
- +1 541-317-1814
- Website
- substancemarket.com
- Category
- Cannabis store
- Status
- Open
- Google Maps
- View on Google Maps
Opening Hours
- Monday8:00 AM – 9:00 PM
- Tuesday8:00 AM – 9:00 PM
- Wednesday8:00 AM – 9:00 PM
- Thursday8:00 AM – 9:00 PM
- Friday8:00 AM – 9:00 PM
- Saturday9:00 AM – 9:00 PM
- Sunday9:00 AM – 9:00 PM
Amenities
Customer Reviews
The atmosphere is very welcoming, everyone is so helpfull, knowledgeable and patient every time my boyfriend or I come in, Erika you are amazing! With such a wide variety of products to choose from. It has become our go to dispensary and will be for years to come. Thank you guys for everything you do!
Casey thank you for the top notch customer service! The sub zero was absolutely bomb and I’ll be back for more. This shop was super friendly and clean and the products are amazing! Thanks again to Casey for helping me choose this flower!
Wonderful store lots to choose from and the best staff ever i came from grants pass please for the love of all that is good open large store in grants pass
Best selection in the valley, if you haven't stopped in you definitely need to. Prices are a little higher than say top shelf but you pay for the selection. Extremely knowledgeable and friendly staff and they have a veteran discount.
Was very clean big and so many yummy stuff I definitely recommend mac n jack and capped out very good and super kind and knowledgeable staff I can't wait to go back whenever I'm in Medford and try there other stores they say they have 4 now it's always nice finding a really goid dispensary that has super nice staff and great prices with awesome product most of them only have one or the other so this one is top 5 on my list and trust me I've been to so many 😀
Frequently Asked Questions
- What are the hours at Substance Medford?
- Monday through Friday 8:00 AM to 9:00 PM, and weekends 9:00 AM to 9:00 PM.
- Where is this Substance location?
- 1749 E McAndrews Rd, Medford, OR 97504.
- Are there other Substance locations?
- Yes — reviewers mention multiple Substance shops across Oregon with consistent service and product quality.
- Does it serve medical patients?
- Oregon licensed dispensaries serve both recreational adults 21+ and OMMP cardholders. Bring valid ID and your card if applicable.