Top Rated Weed Businesses in Des Peres, Missouri (2026)

The highest-rated weed-related businesses in Des Peres, Missouri, ranked by customer reviews and overall rating. Updated 2026-05-20.

  1. #1

    Root 66 Dispensary - Des Peres, MO

    4.9 ★★★★★ (449)

    12095 Manchester Rd, Des Peres, MO 63131, USA

    Cannabis store

    "First time shopper. Got that 20% off. That was great. Bought some gimmies and a 1 gram infused preroll. There was a small issue with my order. I called in and talked to a friendly bud tender. Who..."

    — Tim Croney
    Call View Profile

How We Rank Listings in Des Peres

Our top-rated list is based on customer ratings and review volume. Sponsored listings do not influence rankings on this page. Businesses are ranked by average Google rating, with review count used as a tiebreaker.