Root 66 Dispensary - South Grand, MO

4.7 (619)
Cannabis store St. Louis

About Root 66 Dispensary - South Grand, MO

On South Grand Boulevard in Tower Grove South, Root 66 serves a busy stretch of St. Louis with consistent value pricing across product categories. The 4.7 rating across 619 reviews reflects a steady customer base that responds to deals and management responsiveness. One reviewer who initially left a one-star review updated to five after the manager handled a small issue better than expected, which signals real follow-through. Some shoppers raise questions about staff product knowledge, particularly around THC versus THC-A distinctions, so direct questions at the counter are worth asking if you are precise about cannabinoid content and potency. Open 8 AM to 10 PM seven days a week, which is one of the wider windows in the South City area. A practical stop if you want competitive prices in the South Grand corridor and value managers who respond to customer feedback rather than ignore it after the sale closes.

Customers mention:
  • Manager handles issues well
  • Strong everyday prices
  • Open 8 to 10 daily
  • Ask about cannabinoid specifics

Business Details

Address
3737 S Grand Blvd, St. Louis, MO 63118, USA
Area
Tower Grove South, St. Louis
State
Missouri
Phone
(314) 257-0816
Int'l Phone
+1 314-257-0816
Website
root66cannabis.com/south-grand-location
Category
Cannabis store
Status
Open
Google Maps
View on Google Maps

Opening Hours

  • Monday8:00 AM – 10:00 PM
  • Tuesday8:00 AM – 10:00 PM
  • Wednesday8:00 AM – 10:00 PM
  • Thursday8:00 AM – 10:00 PM
  • Friday8:00 AM – 10:00 PM
  • Saturday8:00 AM – 10:00 PM
  • Sunday8:00 AM – 10:00 PM

Amenities

Payment
  • Debit cards
Parking
  • Free parking lot
  • Paid parking lot
  • Free street parking
Accessibility
  • Wheelchair accessible entrance
  • Wheelchair accessible parking
  • Wheelchair accessible restroom
  • Wheelchair accessible seating

Customer Reviews

Erica

I gave too stars because the place is an acceptable place to shop at but when I hear about underpaid over worked workers it makes me not want to shop there anymore security guards can not keep the place safe if they are over worked they should be getting off of work at scheduled times the managers should be filling in the gaps I'm not sure if I will come back because as a customer I tlk to the people behind the window so we establish a relationship I dont think it's fair for me to spend my money in places like this ...this goes for all unseen workers

T M

Trying to pass THC-A off as THC. Unknowledgable staff. THC-A transfers to only 87% THC when smoked. So you 24% THC-A is coming out at approximately 16% THC. Despite explaining this to staff, I was still given one varity that was mostly THC-A. NOT primary THC. There is a difference. As a visually impaired person I rely on knowledgeable staff to be my eyes. It was only after arriving home with a magnifying glass could I witness this. Over priced. Skip.

Mykala Flournoy

So I wanted to update I did leave a one star review and I have to say the manager did well above what I even would’ve asked him to do to fix a very small issue great people great prices and it’s the most bang for your buck for sure

Dylan Clayborn

Absolutely amazing people the vibe is awesome and this stuff is 🔥 12/10 would recommend any issue and management rights it ASAP

Pagel Heriford

Seriously the best place I have ever shopped. This one and the 24 hour one are the only ones I go to. Hopefully they will start delivering soon, because that would be great for me. (I am disabled)

Frequently Asked Questions

What are the hours?
Open 8 AM to 10 PM seven days a week.
Is the staff knowledgeable about cannabinoids?
Some reviewers note that THC-A versus THC distinctions were not always clearly explained, so ask direct questions at the counter.
How does management handle complaints?
One reviewer updated a one-star to five-star after a manager resolved a small issue above expectations.
Where is the dispensary located?
3737 S Grand Blvd in the Tower Grove South neighborhood of St. Louis.