Root 66 Dispensary – Dogtown, MO
About Root 66 Dispensary – Dogtown, MO
Sitting on Manchester Avenue in the Ellendale pocket of Dogtown, Root 66 keeps long hours every day of the week, opening at 8 AM and running until 10 PM. Over 900 customer reviews average a 4.8, and the same names keep coming up in the feedback. Cedric, in particular, gets repeat shout-outs for steering customers toward good deals and keeping the vibe friendly. The shop attracts a mix of Dogtown locals, commuters cutting through Manchester, and visitors heading to Forest Park. Late-evening hours make it a practical stop for people getting off second-shift jobs or coming back from a night out. The store's reputation rests less on flashy promotions and more on consistent service from a small core of budtenders who know returning customers by name. Good for: West End locals, late-night shoppers, and anyone looking for a neighborhood dispensary that feels more like a regular hangout than a transaction.
- Open until 10 PM daily
- Cedric praised by regulars
- Welcoming Dogtown atmosphere
- Good new-year deals
Photos
Business Details
- Address
- 6660 Manchester Ave, St. Louis, MO 63139, USA
- Area
- Ellendale, St. Louis
- State
- Missouri
- Phone
- (314) 282-7978
- Int'l Phone
- +1 314-282-7978
- Website
- root66cannabis.com/dogtown-location
- Category
- Cannabis store
- Status
- Open
- Google Maps
- View on Google Maps
Opening Hours
- Monday8:00 AM – 10:00 PM
- Tuesday8:00 AM – 10:00 PM
- Wednesday8:00 AM – 10:00 PM
- Thursday8:00 AM – 10:00 PM
- Friday8:00 AM – 10:00 PM
- Saturday8:00 AM – 10:00 PM
- Sunday8:00 AM – 10:00 PM
Amenities
Customer Reviews
Got some pre-rolls, had one, threw up and ended up in hospital for five days. Getting remainder analyzed. Stay safe. Used to have a good selection of gummies but when the stock runs out, it’s gone for good. Used to carry Camino edibles. Very inconsistent. Spent $$$$ at this place.
Cedric was playing that don trip when I came in with good vibes!! And very inviting offered me and my girl some good deals for the new year!! Bout to be groovy baby!!!
Cedric possesses excellent customer service. He made sure I was very satisfied and comfortable with my purchase. Not to mention he’s a good looking young man. Yeah, I will definitely return to Route 66.
Cedrick was amazing! This store is very friendly and service was great
Andrew rocks **Edit** still awesome and Cilian was fantastic. And if I spelt it wrong I am very sorry sir. Haven't been here since they were having the building painted. LOOKS AWESOME! And hell yeah for the veteran parking! Thank you for supporting vets and having up front parking.
Frequently Asked Questions
- What time does Root 66 close?
- Root 66 closes at 10:00 PM every night, with the same 8:00 AM opening time seven days a week.
- Where exactly is the Dogtown location?
- The store is at 6660 Manchester Ave, in the Ellendale neighborhood on the west side of St. Louis near Forest Park.
- Is Root 66 good for first-time cannabis buyers?
- Yes. Reviewers consistently mention staff taking time to explain options and recommend deals rather than pushing pricier products.
- Does the dispensary offer deals or promotions?
- Customers mention seasonal promotions and budtender-suggested deals, especially around holidays and the new year.