Root 66 Dispensary - St. Peters, MO

4.6 (744)
Cannabis store Saint Charles

About Root 66 Dispensary - St. Peters, MO

Open 24 hours every day of the week, this Root 66 location on South St. Peters Parkway stands out for late-night and early-morning availability that few St. Charles County dispensaries match. The 4.6-star average across more than 740 reviews points to a team that holds service quality across all shifts. Raven, the floor manager, plus Amaze and Joshua get named for walking customers through the rewards program and explaining product quality. Holiday hours hold steady, with reviewers specifically thanking staff for Thanksgiving and similar days. Deals get described as amazing, and the convenient location off the highway makes it a frequent stop for shoppers heading through St. Charles County at odd hours. If you need a dispensary that's open at 2 AM or 6 AM, this is one of the few options in the broader St. Louis metro. Consistent service across all hours sets it apart from competitors with shorter windows.

Customers mention:
  • Open 24 hours daily
  • Strong rewards program
  • Open holidays consistently
  • Friendly across all shifts

Business Details

Address
3004 S St Peters Pkwy, St Charles, MO 63303, USA
State
Missouri
Phone
(636) 373-8329
Int'l Phone
+1 636-373-8329
Website
root66cannabis.com/st-peters-location
Category
Cannabis store
Status
Open
Google Maps
View on Google Maps

Opening Hours

  • MondayOpen 24 hours
  • TuesdayOpen 24 hours
  • WednesdayOpen 24 hours
  • ThursdayOpen 24 hours
  • FridayOpen 24 hours
  • SaturdayOpen 24 hours
  • SundayOpen 24 hours

Amenities

Payment
  • Debit cards
Accessibility
  • Wheelchair accessible entrance
  • Wheelchair accessible parking
  • Wheelchair accessible restroom
  • Wheelchair accessible seating

Customer Reviews

Zavion Delgado

My friend just spent 120 dollars and he gets home to realize he's missing part of the order. Not that big of a deal but for time and effort to come back for a 30 minute roundtrip he can't get no courtesy compensation. Id just recommend somewhere else.

Spooky Sock

This place always has amazing deals and great service. It's near my house so I come here often and every single budtender knows their stuff and is super helpful. Love the product and the staff!

Sabrina Boland

Love this location and the people. My 1st experience was using the pre-order/window option, which I loved. It was quick and friendly. Since that time, I have been in the store, and was happy with the customer service and the available products. Maybe define the 'areas of service' with more distinct signage?

Lay

Root66 is by far the best dispensary that I have been to. Deals are amazing, and the location is super convenient and being open 24/7 is a huge plus. I stopped by today on Thanksgiving and the workers that helped me were incredibly friendly and helpful the entire time. The workers always make the experience better! Highly recommend.

Alexia Devine

I had an amazing experience at Root 66! Raven, the floor manager, was incredibly helpful and really took the time to break down the rewards program and explain the quality of their products. The vibes are always great here—good energy, good people, and consistently excellent customer service. Shoutout to Amaze and Joshua as well for being so attentive and making the visit even better. Highly recommend this dispensary!

Frequently Asked Questions

Is Root 66 St. Peters really open 24 hours?
Yes — the dispensary operates 24 hours every day of the week, including holidays.
Where is Root 66 St. Peters located?
Find it at 3004 S St Peters Pkwy in St. Charles, Missouri, serving the broader St. Peters area.
Does Root 66 have a rewards program?
Yes, and reviewers specifically credit floor manager Raven for explaining the rewards system clearly to new customers.
Is Root 66 open on holidays?
Yes — customers specifically mention shopping on Thanksgiving and being helped by friendly staff during holiday hours.