Cannabis Headquarters
About Cannabis Headquarters
Patients in Tupelo can pick up at one of the longest schedules in Mississippi: 8 AM to midnight Monday through Saturday at 608 North Gloster Street, with Sunday hours from 10 AM to 8 PM. That schedule alone makes Cannabis Headquarters the default option for picking up after work, after dinner, or on a late shift. Budtenders Gretta and Greda get specific praise for terpene education and helping patients understand how product profiles translate to actual effects. The shop carries flower, edibles, vapes, and concentrates at prices reviewers describe as competitive across central Tupelo. Products tend to display openly, which fits patients who want a visual cue before buying. With a perfect 5-star rating across 239 reviews, this shop has built genuine repeat business in a city saturated with dispensary options. Late-night accessibility plus knowledgeable staff is a rare combination in Mississippi medical cannabis retail.
- Open until midnight six days weekly
- Strong terpene-focused customer education
- Visible product displays for browsing
- Competitive pricing across the menu
Business Details
- Address
- 608 N Gloster St, Tupelo, MS 38804, USA
- State
- Mississippi
- Website
- cannabisheadquarter.com
- Category
- Cannabis store
- Status
- Open
- Google Maps
- View on Google Maps
Opening Hours
- Monday8:00 AM – 12:00 AM
- Tuesday8:00 AM – 12:00 AM
- Wednesday8:00 AM – 12:00 AM
- Thursday8:00 AM – 12:00 AM
- Friday8:00 AM – 12:00 AM
- Saturday8:00 AM – 12:00 AM
- Sunday10:00 AM – 8:00 PM
Amenities
Customer Reviews
The best place for your needs...BY FAR! Couldn't ask for a nicer group of bud tenders! Let Greda know what you need, she'll take care of you!
Greda was great. I won a drawing and scored a coupon book. It's also a homemade comic book that she made. I freaking love it.
Greda was so fun to talk and had a great personality. She was super informativeabout the products, answered all of my questions leading me to learn something new about terpenes.😁 Great customer service I will definitely be back in the future.
Tried this place for the first time and was pleasantly surprised. The products were all visibly displayed and the employee was very knowledgeable.
I had a great experience and the prices were awesome but best of all was Gretta,she was extremely knowledgeable and helpful,definitely going back!!!
Frequently Asked Questions
- Where is Cannabis Headquarters in Tupelo?
- The shop is at 608 North Gloster Street, Tupelo, MS 38804, on North Tupelo main commercial route.
- What hours does Cannabis Headquarters keep?
- Monday through Saturday 8 AM to midnight and Sunday 10 AM to 8 PM, one of the longest schedules in Mississippi.
- Is Cannabis Headquarters open late?
- Yes. The shop runs until midnight Monday through Saturday, making it the go-to for late-night patient pickups in Tupelo.
- What does Cannabis Headquarters carry?
- Flower, pre-rolls, edibles, vapes, and concentrates from Mississippi-licensed cultivators and processors.